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a female nurse who is in the same room when a female patient is examined by a male doctor, or a police officer who protects a person injured by a criminal when they are in public
(especially in the past) to stay with and take care of a young woman who is not married when she is in public:
The reason for this is that, at present, there is no k n o w n mechanism to explain how cells can secrete molecular chaperones.
Therefore, pharmacological chaperones show great promise as a new class of therapeutic agents that can be specifically tailored for a particular genetic disease.
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A related strategy for the treatment of various protein-misfolding disorders is to rescue folding defects with “pharmacological chaperones”.
The processing defects must be identified and tested to determine whether they can be rescued with pharmacological chaperones.
The girl of the period demands increased liberties, including the right to entertain without chaperones, to wear cosmetics, and to dress in stylish fashions.
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Thus, i t was possible that these findings were not d u e to the molecular chaperones themselves, b u t to contaminating bacterial components.
Many researchers worldwide are attempting to determine the mechanism of action of these various molecular chaperones, many of which exist as families of related proteins.
Initial clinical studies with pharmacological chaperones have successfully reduced clinical symptoms of disease.
The advantages of pharmacological chaperones are that they can be specific and nontoxic, and can be used at much lower concentrations than chemical chaperones.
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